منابع مشابه
Histidine biosynthesis.
Histidine (His) is one of the standard amino acids in proteins, and plays a critical role in plant growth and development. The chemical properties of the imidazole side group allow His to participate in acid-base catalysis, and in the co-ordination of metal ions. Despite the biological importance of this molecule, His biosynthesis has been somewhat neglected in plants, in stark contrast to micr...
متن کاملThe Biosynthesis of Histidine
It was later shown (2) that the mutant C84 accumulates imidazoleglycerol’ in the growth medium, that mutant Cl41 accumulates imidazoleglycerol and imidazoleacetol,2 and that T1710 accumulates L-histidinol.3 It was also observed that none of these compounds will replace histidine in promoting the growth of these mutants or other mutants blocked earlier in the sequence. This suggested that these ...
متن کاملThe first step of histidine biosynthesis.
In a continuation of work on gene-enzyme relationships in histidine biosynthesis (1, 2) we have examined the early steps of the biosynthetic pathway in Salmonella typhimurium. It has been found that the first enzyme of the pathway catalyzes the condensation of 5-phosphoribosyl-1-pyrophosphate and adenosine triphosphate to form pyrophosphate and a product which has been isolated and characterize...
متن کاملGenetic dissection of histidine biosynthesis in Arabidopsis.
The biosynthesis of histidine (His) in microorganisms, long studied through the isolation and characterization of auxotrophic mutants, has emerged as a paradigm for the regulation of metabolism and gene expression. Much less is known about His biosynthesis in flowering plants. One limiting factor has been the absence of large collections of informative auxotrophs. We describe here the results o...
متن کاملPhosphoribosyladenosine Monophosphate, an Intermediate in Histidine Biosynthesis.
The first reaction of histidine biosynthesis, the conversion of 5-phosphoribosyl-1-pyrophosphate and adenosine triphosphate to N-1-(5’-phosphoribosyl)-ATP has been described previously (1, 2). The present report describes the preparation, isolation, and characterization of N-1-(5’-phosphoribosyl)-AMP, the second intermediate in the pathway (Fig. 1). This compound is formed from phosphoribosyl-A...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: EcoSal Plus
سال: 2009
ISSN: 2324-6200
DOI: 10.1128/ecosalplus.3.6.1.9